Overcoming Analytical Challenges in Next-Gen Cancer Therapies
What you will learn
Key Analytical Challenges
Gain insights into the unique analytical challenges associated with each component of an ADC — antibody, linker, and payload — covering aspects like structural integrity, stability, and targeted delivery
Critical Role of Drug-to-Antibody Ratio (DAR)
Understand the importance of maintaining a consistent DAR in ADC development to balance potency and minimize toxicity, including methods for accurate DAR measurement and distribution analysis.
Optimizing Cell-Based Bioassays
Learn about the role of cell-based bioassays in evaluating ADC potency, with tailored assay designs to account for biological variation, drug concentration, and target cell response.
